BDBM373779 4-((1-benzylpiperidin-4-yl)amino)-3-chloro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide 2,2,2-trifluoroacetate::US10246453, Example 46::US10662184, Example 46::US10815229, Example 46::US11299490, Example 46

SMILES Clc1cc(ccc1NC1CCN(Cc2ccccc2)CC1)S(=O)(=O)Nc1ncns1

InChI Key InChIKey=CUVFBZYYXBHMTR-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 373779   

TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM373779(4-((1-benzylpiperidin-4-yl)amino)-3-chloro-N-(1,2,...)
Affinity DataIC50: >3.00E+4nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM373779(4-((1-benzylpiperidin-4-yl)amino)-3-chloro-N-(1,2,...)
Affinity DataIC50: >3.00E+4nMAssay Description:In general, Trex HEK293 cells were stably transfected with an inducible expression vector containing the full-length cDNA coding for the desired huma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent